We've heard that the Taxol is a lot easier. TAXOTERE safely and effectively. Avoid raw fruits, vegetables, whole grain bread, cereals, and seeds. We are all stronger than we think and even stronger than we give ourselves credit for! I haven't had much information about that yet. Avoid the sun between 10-2 pm, when it is strongest. If you feel unwell or have any of these signs, tell them straight away. My reaction to Taxol was different. By 2010, the drug had . The pain is horrendous and for me it moves from anywhere to anywhere. My wonderful wife took me away between chemo and Rads, it was a truly enjoyable break, 5 days in a cabin in the woods (provided free by The Willow Foundation). If the count gets too low, you may receive a blood transfusion. This is the start of my second week and although the bone aches have settled, the stomach is at it's worst with terrible cramps and pains. Since the growth of normal cells may also be affected by docetaxel, other unwanted effects will also occur. Docetaxel also was found to be highly effective in patients with a poor prognosis, having metastases in three or more organs (53%), and/or visceral sites of disease (47%). Gone too far now to stop just need to finish the course. I have weaned myself off the Co-Codamol as I don't want to rely on it and the bone aches have reduced considerably now. Ask for Zomorph and Oramorph for your bone and joint pain, if it doesn't help ask for Fentynal patches. xx, Just back from my Oncology appointment before cycle 5 of Docetaxel, they have decided to reduce the strength of the dose due to all the side effects and length of time they lasted on cycle 4. Taxotere injections can cause your white blood cell levels to plummet. You should feel a lot better in about a week's time. No wonder you were dreading it. However, our monthly flat rate of just $49 per medication . So close to week three now, exercise nil, so bored with all the sofa days. This can get progressively worse with additional doses of the medication. Around that time I had violent throw up for a couple of sessions, and then that was it. I am just unfortunate to get them all. I often feel like it's too much and want to give in. In its mechanism of action, Taxotere prevents the inner structures of cancer cells from building, which stops cell division and eventually leads to cancer cell death. You may dislike foods or beverages that you liked before receiving cancer treatment. Brady appears to be expanding his brand rapidly in 2023. Men initially treated with Taxotere had favorable outcomes compared to those who were initially treated with Novantrone: Median overall survival was 22 months for men treated with Taxotere first and 15 months for those treated with Novantrone first. I don't want to put anyone off this treatment as I know it works wonders on the tumour , we all react differently as previously advised on here, but I want understand where I went wrong and what I can do to prepare myself for the next cycle. That's really great that she had that positive response though, seems worth it and hopeful for the rest of us! I did not start feeling better until the 5 or 6th day after chemo. I had cisplatin , taxotere and the neulastra shot and really hurt the 1st infusion but not the others after starting the clariton. So I queried the need for the remaining 2 docetaxel. Common side effects of Tax are bone aches and pains, sore mouth/mouth ulcers, oral thrush, loss of taste. Taxotere is a chemotherapy drug that is used to treat various cancers such as breast cancer, non-small cell lung cancer, prostate cancer, gastroesophageal cancers, and head and neck cancers. This study found that women diagnosed with hormone-receptor-positive breast cancer did benefit from getting a taxane. The end is now in sight and just keep thinking what a good job the chemo is doing getting rid of this nasty disease. Some brief shopping time to restock for the next session. Patients were treated in weeks 1, 3, and 5 with doxorubicin 20 mg/m2 as a 24-hour intravenous infusion on the first day of every week in combination with ketoconazole 400 mg orally 3 times a day daily for 7 days. Do not use a razor (an electric razor is fine). But I'm on SSP and we can't afford to have him stay at home every time I feel ****. I mentioned this thread to her - the common wisdom that the first is the worst because of the uncertainty and the rest is more of the same, only more so. Try saltines, or ginger ale to lessen symptoms. I had the sore mouth too but I must have been one if the lucky ones as I do not remember too many other side effects - it was 7 years ago. Do not eat grapefruit or drink grapefruit juice during the 2 days before, the day of, and two days after each dose. Performing regular mouth care can help prevent or manage mouth sores. Docetaxel can cause your body to hold too much fluid, which can be a serious side effect. Taxotere Side Effects If you or a loved one want to prepare and learn about the worst days on Taxotere, many patients often receive Taxotere in combination with other chemo drugs. If you feel unwell or have any of these signs, tell them straight away. I just had my first Docetaxal dose over a week ago.. Have you rang your chemo hotline? The most common side effect in day-to-day life is fatigue. Perseverance!! Taxotere Chemo: April 29 2010 May 20 2010 June 10 2010 July 1 2010. Operation will be 4 weeks after my last dose. I have at times reached my lowest and questioned if I can continue to put my body through this poison. Hair generally starts to regrow soon after treatment is completed. My experience was that how I felt after my following treatments was similar to my reaction after the first treatment. This chemo certainly throws everything at us to endure. Keep your fingernails and toenails clean and dry. I know it is really hard to go back when you know how rough it will make you feel-I tried to look at as a bad dose of flu( a normal person problem)No one would expect you to get out of bed with flu. Stay well hydrated. Nails still ok, feet and nails need constant cream sessions. The steroid is given in pill form or by IV, which will be determined by your healthcare provider. Really, you already have otherwise you wouldn't be 4 sessions down with only 2 more to go. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling . They all worked with the FEC but this new chemo is so much harsher on my mouth. It can be given alone or with other drugs. If you or a loved one want to prepare and learn about the worst days on Taxotere, many patients often receive Taxotere in combination with other chemo drugs. Chemo nurses kept pushing me to take strong painkillers.I survived with only half tablets at night. Fluid build-up can cause heart failure and poor blood circulation. I have lost ALL taste buds. As long as I moved and tried to do those things, even though I felt crappy, I would always feel better afterwards. As the treatments go on by the 4th one, it took me a few more extra days to get some energy. 2.6 Premedication Regimen. Severe symptoms are less common but require dose modifications. Most of the hard work is done, you just need to push a little harder to finish the race! This combination of meds had the remarkable result of shrinking my very large tumor by a full 50 percent! In 2022 . It is used as a treatment for various cancers, most notably breast cancer. [Verse 1] Valentine's Day, the worst day, got too many to please Spent over a hunnid Gs and she still wasn't pleased I done gave her a hundred Gs, all she want is me It's a treat when we meet up . Take regular Paracetamol and Ibruprofen all day every day. Then I had actual vomiting, first time ever, because the medications have upset my stomach. Found the freeze gell hit the joint areas better and gave relief. neuropathy, or pain caused by nerve damage. Then I will start on radiotherapy. : those who have a cold, fever or cough or live with someone with these symptoms). Make sure she is getting alot of water, eat fruits and vegetables. I have finished 4 cycles so far with 4 more to go. I struggle to drink which I know makes things worse. Best advice is to ring your care team/chemo unit asap and definitely before you go for your next treatment and tell them everything you are feeling/suffering from. I lost my hair and everything, but the chemo itself was not that bad. I will speak to nurses but most of what I am going through is normal side effects for the Docetaxel chemo. It doesnt have to be anything big. I had my first Taxotere on Monday and am not coping at all. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. They didnt feel great, but it wasnt bad. For your mouth get som kingingical mouth wash and rinse with salt water every hour or so. Taxotere is part of a family of drugs known as taxanes that work by preventing cell growth. If red meat is a problem, eat chicken, turkey, eggs, dairy products, and fish without a strong smell. Get comfortable, own the sofa, the remote, get a body pillow, blanket, soft pyjamas, sweets to suck on, films to watch & any other essential supplies! Weirdly, her pain would only come on around 3pm-6pm, then her temp would spike like crazy too. While we were driving home - it's a nice, sunny, fairly warm day - Moopy observed that getting out was a reminder of what our life will be like again. Your story kinda reads similar to my wife's when she was on Docetaxel. Let your oncology care team know if you have any excess bruising or bleeding, including nose bleeds, bleeding gums or blood in your urine or stool. I would go to work when I was able to and just did what I could. Its often very difficult to treat edema caused by cancer and chemotherapy. Humor can also lessen anxiety and discomfort, allowing cancer patients to talk more openly about their concerns and fears. Also, try eating low-fiber, bland foods, such as white rice and boiled or baked chicken. If you do not have a bowel movement for 2-3 days, you should contact your healthcare team for suggestions to relieve constipation. I ended up in hospital with spiked temperature, although nothing showing in my bloods, but tremendous discomfort and feeling very unwell. I only have one more left now as it was my 5th cycle of chemo regimen FEC x 3 then Docetaxel x 3 . You may notice dry skin or changes in the color or tone of your skin. Saying goodbye to our 8th graders and saying" In addition, dietary changes may help. The taste improved just before the next treatment. Remember your reason for starting chemo. My own experience to date As of day 8 after my first Tax blast, I currently hate Tax and FEC in equal measure. If you experience nausea, lack of appetite, or other eating problems, discuss solutions with your doctor or nurse navigator. I thought I would need to have it for three weeks but they have said 5 days as new research has shown that it works just as well as the three weeks. He recommended that I halve the dose, but I'd had previous allergic . At one point, they had to give her liquid morphine as the joint pain was so bad. Make sure that those around you understand that while the pain peaks, you need absolute rest. This hair loss can be all body hair, including pubic, underarm, legs/arms, eyelashes, and nose hairs. You should not drive after the infusion until you know how it will affect you. I finished T & C on April 1 (total of 6 treatments). I had four rounds of Herceptin, Carboplatin, and Taxotere. My diet is so bland in taste no matter what I try, if the mouth problem resolves and I can enjoy a varied diet maybe my stomach will settle better. I had the first T on Wednesday, was too sick to work come Monday, even worse come Thursday and in Hospital with Sepsis come Friday! You have given me some great pointers and hopefully I can be calmer about my next 2 cycles. At least with experiencing this cycle we will be more prepared. Hope you are all doing well with your journey and keeping well. Taxotere is a mitotic inhibitor that interferes with your bodys cell division process. Many people lose alltheir body hair, including their eyebrows and eyelashes. When meds say 'Take with food' a couple of biscuits or something similar is enough. Yes you will have have to have the G - CSFinjections for the bone marrow stimulation after the Docetaxal chemotherapy - the same as the FEC. A little morning nausea for first week, a few headaches and sore lips. xx, No problem you keep strong & you will get through it, I've never cried so much in my life I think it was my way of dealing with it. An absolutely horrid drug. The dosage and schedule are determined by the person's size and type of cancer. You won't be up to doing anything. ), and have smoked and used alcohol for most of my life. My doctors have been very good and have assured me that they caught it early. I don't know about AC, but when I was on TC, I was told that it's not cumulative, so I would not be feeling worse as chemo progressed.Good luck to Donna, I hope she gets the rest she needs. If your mouth becomes dry, eat moist foods, drink plenty of fluids (6-8 glasses), and suck on sugarless hard candy. In some ways was easier, in others was more taxing (pun intended)! After starting docetaxel, many men experience the improvements in disease-related symptoms, including pain, fatigue and loss of energy. Have had one cycle of that and have the second next week. (I too read somewhere that grapefruit can make the side-effects of the drug worse). Your physician will order lab tests throughout your treatment to keep an eye on your levels. Give yourself credit for getting this far. And there is no normal feeling throughout the 3 weeks. Mike White. Get the B**tard out for good! His consultant advised small walks to begin the process of getting the muscles going (started with walking up and down our lounge before he managed the outside!! Progression-free survival was 2-3 months for both groups. It is a combination of two chemotherapy medicines: Docetaxel (Taxotere) Cyclophosphamide (Cytoxan) Docetaxel is a type of chemotherapy medicine called an taxane. Thinking of you and your family, best wishes. Hope you are well now too. In some people, the symptoms slowly resolve after the medication is stopped, but for some, it never goes away completely. You'll get there too. I've dealt with everything they have thrown at me with a really positive attitude ( including discussions about possible having to have a double mastectomy due to genetics and a failed pre chemo IVF attempt), but I'm at a loss with what to do with myself at the moment. Certain cancer treatments can cause sores or soreness in your mouth and/or throat. Researchers spent YEARS finding chemotherapy compounds that could attack prostate cancer cells. It has now been almost exactly 4 days (96 hours) since. I'm taking Codeine and paracetamol with little effect. xx, I too had terrible 1st cycle and likewise was admitted due to high temp feel better now but due next cycle on we'd feeling scared I have 3 very young children am incurable breast cancer not sure can cope am now on injection to keep blood count up, Sorry to hear of your experience Jazzy, I know it's not pleasant. Fatigue is very common during cancer treatment and is an overwhelming feeling of exhaustion that is not usually relieved by rest. An absolute pleasure to have helped. The cycles were repeated every 3 weeks for 3 . Each mL contains 40 mg docetaxel (anhydrous) and 1040 mg polysorbate 80. No cancer cells were found, and she was deemed "no evidence of disease". I had my 2nd cycle of Docetaxel yesterday. Worst days when i was on 3chemo meds, taxotere, carbon, and Herceptin, were 3-5 days after. Your fingernails/toenails may become dark, brittle or fall off. xx, My consultant reduced my injection strength so I had to endure 10 injections as prescribed. I was diagnosed in August with Breast cancer. It belongs to a drug class called taxanes. If this were to happen, the only fix is an invasive surgery. We think its important to know what you might expect on your worst days on Taxotere. So got it again. On 9-1-09, I finished 6 cycles of Taxotere, Carboplatin and Herceptin. Avoid large crowds and people who are sick (i.e. Bacon, ham, and onion can add flavor to vegetables. I asked my Oncologist if there was any alternative as the side effects are so awful, but there isn't. So I feel that is a positive thought. I have had problems with temperaturechilly and drafts set off cough and shivering, warm and cosy sweating. Avoid drinking alcohol on the day of your Taxotere injection. I'm just shellshocked by it all but I'm glad I was just finished my full treatment for breast cancer after 10 years. I was so tired, and I wasnt expecting that level of fatigue. So always stay in touch with the team.. Im out now on antibiotics.. Men who are treated with this medication should use effective birth control during and for 4 months after the last dose. I was 'tired' on days 3 & 4 on A/C but napping/resting helped. I completely avoided this by doing a few things (recommended by American and French oncologists, and also by many girls who have had the courage to try these things). Really sorry to read that you having such a s---- time with your current chemo treatment. starting at end of cisplatin infusion (2.4)See full prescr ibing information for TAXOTERE. Repeat cycle every 3 week. A swift and successful op was followed by FEC-T chemo. 83 Likes, 0 Comments - Marley Foster (@marley._.foster) on Instagram: "The last few days of school were probably the worst. Keep well. You are not alone in this. Good luck , The first dose of docetaxol was the worst for me. I know now that I am being too hard on myself and putting on a brave face, it's good to let my emotions make sense of the turmoil I was feeling. Notify your oncology care team if your mouth, tongue, inside of your cheek or throat becomes white, ulcerated, or painful. Sun sensitivity can last even after chemotherapy is completed. I spent yesterday in A&E with chest pains which turned out to be heartburn and anxiety. 2.4 ) See full prescr ibing information for taxotere bowel movement for 2-3 days, you absolute... 10 injections as prescribed may receive a blood transfusion bone aches and pains sore. Take regular Paracetamol and Ibruprofen all day every day how it will affect you common effects... Was similar to my wife 's when she was on 3chemo meds, taxotere, carbon, and taxotere information. Work by preventing cell growth & 4 on A/C but napping/resting helped morning for... 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